NIST Technicalendar February 26 to March 2, 2007 The NIST Technicalendar is issued each Friday. All items MUST be submitted electronically from this web page by 12:00 NOON each Wednesday unless otherwise stated in the NIST Technicalendar. The address for online weekly editions of the NIST Technicalendar and NIST Administrative Calendar is: http://www.nist.gov/tcal/.
Please evaluate the web Technicalendar using our 30 Second Evaluation

In this Issue: Meetings at NIST Meetings Elsewhere Announcements Talks by NIST Personnel NIST Web Site Announcements NIST Administrative Calendar (current)   NIST Vacancy Announcements (current)

Also available: Previous Issues of the Technicalendar Quick Technicalendar (current) Last week's Quick Technicalendar Last week's Technicalendar Detailed Search NIST Journal of Research (Current TOC) Change User Options

1:45 PM - Black History Month Event Honoring Dr. Percy L. Julian

10:30 AM - Cold atoms in a two-period optical lattice: a tool for quantum information and correlated many body physics
10:45 AM - Magnetic Order and Spin Dynamics in (RareEarth)2PdSi3 Compounds
3:00 PM - Phage Display: Combinatorial Material Science on the Cheap

10:30 AM - Probe Level Models for Microarray Data
10:30 AM - A Perspective on Open Standards: Implications for Interoperability in Design and Manufacturing
11:00 AM - ROSE: Compiler Infrastructure for Custom Software Analysis and Transformation

10:30 AM - Electron Conducting States in Nano- and Mesoscale Molecular Devices
3:00 PM - Water at Local Scales
3:00 PM - Water at Local Scales

10:30 AM - Sequence-Resolved Detection of Pausing by Single RNA Polymerase Molecules
10:30 AM - Design and Fabrication of the Waldseemueller Map

2/26 -- MONDAY

1:45 PM - CHEMICAL SCIENCE AND TECHNOLOGY LABORATORY OFFICE SEMINAR: Black History Month Event Honoring Dr. Percy L. Julian
Our Black History Month event will honor Dr. Percy L. Julian with the airing of the NOVA film "Percy Julian: Forgotten Genius." The program for the event is below. 1:45pm Welcoming Remarks: Dr. William Jeffrey, Director, NIST Commentary - Dr. James P. Shoffner, American Chemical Society - Dr. Bernhard Witkop, National Academy of Science 2:00pm Airing of NOVA Documentary “Percy Julian: Forgotten Genius” 4:00pm Gaithersburg, MD Attendee’s Reception Employee Lounge
James Shoffner , American Chemical Society. Bernhard Witkop , National Academy of Sciences.
Administration Bldg, Red Auditorium. (NIST Contact: Willie May, 301-975-8300, wem@nist.gov)
Special Assistance Available


2/27 -- TUESDAY

10:30 AM - ATOMIC PHYSICS DIVISION SEMINAR: Cold atoms in a two-period optical lattice: a tool for quantum information and correlated many body physics
I will describe recent experiments studying ultra-cold atoms in a dynamic, double-well lattice. Using this lattice, we are able to isolate arrays of atom pairs, and separately control the internal states of the atoms in each pair. By controlling interactions between the atoms we are able to induce controlled interchange of the spin and spatial quantum numbers between the two atoms, the essential feature of a quantum SWAP gate. Such a lattice provides a test-bed for ideas in neutral atom quantum computing, and a flexible platform for simulating correlated many-body physics.
Dr. Trey Porto , Physicist, NIST.
221 Bldg, Rm. B-145. (NIST Contact: Ben Brown, 301-975-4841, ben.brown@nist.gov)

10:45 AM - NIST CENTER FOR NEUTRON RESEARCH SEMINAR: Magnetic Order and Spin Dynamics in (RareEarth)2PdSi3 Compounds
Michael Loewenhaupt , Technical University Dresden.
Bldg. 235, E100 (Large Conf. Room). (NIST Contact: J. Lynn, 301-975-6246, jeff.lynn@nist.gov)

3:00 PM - POLYMERS DIVISION SEMINAR: Phage Display: Combinatorial Material Science on the Cheap
Increased accessibility to genetic engineering methods has led to a proliferation of new tools into traditional material science applications. One of these tools is phage display which has emerged as a powerful method to identify peptide motifs with high affinity and specificity. This presentation intends to inform the audience of our division capabilities, the latest in material science applications, and our goals, motivation and recent results in targeting hydroxyapatite and amino-acid derived polycarbonates for use in tissue engineering applications.
Matt Becker , NIST.
Polymer Building, Room A312 CR. (NIST Contact: Jan Obrzut, 301-975-6845, jano@nist.gov)


2/28 -- WEDNESDAY

10:30 AM - STATISTICAL ENGINEERING DIVISION SEMINAR: Probe Level Models for Microarray Data
High density oligonucleotide expression arrays are widely used in many areas in biomedical research. In this technology, a number of critical steps are required to convert the raw measures into the data relied upon by biologists and clinicians. These data manipulations, referred to as preprocessing, have enormous influence on the quality of the ultimate measurements and studies that rely upon them. In this talk I will review the major preprocessing steps and present a statistical framework on probe level data that applies to most microarray applications. Examples of model based preprocessing procedures for gene expression data and unified method that integrates preprocessing into the standard statistical analysis flow of microarray data will be shown.
Zhijin (Jean) Wu , Assistant Professor of Biostatistics, Brown University.
Chemistry Building, Room A240. (NIST Contact: John Lu, 301-975-3208, john.lu@nist.gov)

10:30 AM - MANUFACTURING SYSTEMS INTEGRATION DIVISION SEMINAR: A Perspective on Open Standards: Implications for Interoperability in Design and Manufacturing
S Rachuri , MSID/MEL.
Metrology Bldg, Rm. B105. (NIST Contact: S. Rachuri, 301-975-4264, rachuri.sudarsan@nist.gov)

11:00 AM - SOFTWARE DIAGNOSTICS AND CONFORMANCE TESTING DIVISION SEMINAR: ROSE: Compiler Infrastructure for Custom Software Analysis and Transformation
ROSE http://www.llnl.gov/CASC/rose/ is a tool for building source-to-source transformation tools for the custom analysis of large scale C and C++ applications. ROSE represents a mechanism to build translators that read the user's application source code and output highly optimized or customized C or C++ code. ROSE is the compiler-framework which permits library or application developers to build their own domain-specific source-to-source analyzers/translators. The specification of transformations is made as easy as possible with non-compiler people as a target audience. Custom analysis of large scale applications is also simple to specify; ROSE supports a number of standard program analysis phases common to typical compilers, and is particularly focused on being easy to use. ROSE is an Open Source project, supporting large scale DOE applications and includes substantial documentation. The output from a translator built from ROSE is itself C++ code (but transformed using customized analysis and transformations). The result is a compile time mechanism that leverages/wraps any vendor's compiler, but provides for highly specialized custom domain-specific analysis and/or optimizations. This work forms a part of research work on optimization and Cyber-Security. A specific goal is to wrap numerous vendor compilers with a security analysis reporting layer that will address Cyber-Security specific concerns within the software development process. Current work is also focused on source code security analysis research using the ROSE framework to provide complete access to the C or C++ source code of applications supporting automated analysis and corrective steps. This is part of research work with UC Davis. Recent work has focused on how to build whole program analysis tools (greatly simplifying security analysis of large scale applications consisting of hundreds of file). Ongoing work focuses on the representation of security flaws across multiple languages and how to identify them in source code. We would be particularly interested in collaborations involving source code security analysis. This talk will present ROSE, some of the recent research, and examples of the use of ROSE along with opportunities for research collaborations. We will present the ongoing work on Cyber-Security and discuss ROSE mechanisms well suited to supporting general security analysis of large scale applications.
Daniel Quinlan , Lawrence Livermore National Laboratory, Livermore, CA, dquinlan@llnl.gov.
222 Bldg, Rm. B321. (NIST Contact: Vadim Okun, 301-975-3268, vadim.okun@nist.gov)


3/1 -- THURSDAY

10:30 AM - CNST SEMINAR SERIES: Electron Conducting States in Nano- and Mesoscale Molecular Devices
Organic materials can offer new electronic functionality not available in the inorganic devices. However, the integration of organics within nanoscale electronic circuitry poses new challenges for material physics, chemistry and nanofabrication. I will discuss different approaches to engineer useful electronic properties in small molecular devices. In the first case, the electronic functionality is to be provide by the backbones of short molecules. We have developed a set of fabrication and characterization techniques allowing us to build devices with self-assembled monolayers from nearly single-molecule size up to ~300nm on a side. In the second approach, we build devices with monolayers of macromolecules. The electronic properties are determined by the composition, the chemical conversions and electric-field-induced chemical reactions of the side groups.
Nikolai Zhitenev , Bell Labs., Alcatel-Lucent, Murray Hill, NJ, zhiten@alcatel-lucent.com.
215 Bldg, Rm. C103-C106. (NIST Contact: Joseph Stroscio, 301-975-3716, joseph.stroscio@nist.gov)

3:00 PM - CERAMICS DIVISION SEMINAR: Water at Local Scales
Robert Szoszkiewicz , Columbia University.
215 AML Bldg, Rm. C103-C106. (NIST Contact: Robert Cook, 301-975-3207, robert.cook@nist.gov)

3:00 PM - CERAMICS DIVISION SEMINAR: Water at Local Scales
In this talk I resume our investigations of local capillary bridges of water, and water confined in sub-nanometer gaps. Local water capillary bridges play an important role in micro- / nano- mechanical systems, as well as in dip-pen nanolitography. Water in sub-nanometer gaps defines fundamental physics of ion channels inside each cell membrane. Our atomic force microscope (AFM) friction measurements in air on hydrophilic samples show how and why it is possible to tune the water capillary bridges in a predictable way, and validate the water gas-liquid phase diagram at nanoscopic lengths [1]. We show that stretched water bridges are in mechanical equilibrium with the external pull-off force acting at the contact, but not in thermodynamic equilibrium with the water vapor in air [2]. In the kinetics study, we find that local water menisci need up to a few ms to nucleate between a hydrophilic glass surface and AFM tips with curvature radius below 50 nm at typical room conditions, e.g., temperature between 332 K to 299 K, 40 % relative humidity [3]. Molecular dynamics (MD) simulations, however, for much smaller tips (curvature radius below 5 nm) produce several orders of magnitude smaller nucleation times presumably due to water diffusion barriers at the local scales [4, 5]. Combined experimental and theoretical investigations of the forces encountered by an AFM tip approaching a solid surface in purified water mimic water confined in nano-gaps [5]. For tip-sample distances between 0 +/- 0.03 nm to 2 nm, we find oscillatory solvation forces for hydrophilic surfaces (mica, glass), and less pronounced oscillations for a hydrophobic surface (graphite). The MD simulations reveal layering of the confined water density and the development of hexagonal order in layers proximal to a hydrophilic surface of glass. For sub-nanometer water films confined between hydrophilic surfaces, the experiments show four orders of magnitude increase of water viscosity with respect to the bulk, which agrees with a simulated sharp decrease in the diffusion constant. [1] R. Szoszkiewicz, E. Riedo, APL 87, 033105 (2005) [2] L. Sirghi, R. Szoszkiewicz, E. Riedo, Langmuir 22, 1093 (2006) [3] R. Szoszkiewicz, E. Riedo, PRL 95, 135502 (2005) [4] R. Szoszkiewicz, J. Gao, E. Riedo and U. Landman, in preparation [5] T.-D. Li, J. Gao, R. Szoszkiewicz, U. Landman, E. Riedo, accepted in PRB (2007)
Robert Szoszkiewicz , Columbia University.
215 AML Building, Rm. C103-C106. (NIST Contact: Jaroslaw Grobelny, 301-975-6104, jaroslaw.grobelny@nist.gov)


3/2 -- FRIDAY

10:30 AM - SYSTEMS BIOLOGY SEMINAR SERIES: Sequence-Resolved Detection of Pausing by Single RNA Polymerase Molecules
We apply an ultrastable optical-trapping assay to follow the motion of individual molecules of RNA polymerase (RNAP) transcribing templates engineered with repeated sequences carrying imbedded, sequence-specific pause sites of known regulatory function. Both the known and ubiquitous pauses appeared at reproducible locations, identified with base-pair accuracy. Ubiquitous pauses were associated with DNA sequences that show similarities to regulatory pause sequences. Data obtained for the lifetimes and efficiencies of pauses support a model where the transition to pausing branches off of the normal elongation pathway and is mediated by a common elemental state, which corresponds to the ubiquitous pause. This result complements single-molecule studies,which showed that bacterial RNAP pauses frequently during transcriptional elongation; our results clarify the relationship of these 'ubiquitous' pauses to the underlying DNA sequence.
Arthur LaPorta , Dept. of Physics and Institute for Physical Science and Technology, University of Maryland, College Park, MD.
Radiation Physics Bldg, Rm. C301. (NIST Contact: Charles Clark, 301-975-3709, charles.clark@nist.gov) http://physics.nist.gov/sbss
Special Assistance Available

10:30 AM - ,,,,NIST CHAPTER OF SIGMA XI SEMINAR: Design and Fabrication of the Waldseemueller Map
In the 1950s, NBS lead the project to build glass boxes to hold the U.S. Charters of Freedom - the original Declaration of Independence and the U.S. Constitution. In 1998 the National Archives and Records Administration again came to NIST with a request to build new encasements for these precious documents. This project was completed in 2003 and the new encasements are now on display at the National Archives in Washington DC where close to a million visitors a year see these documents. Because of these experiences and the broad scientific and engineering expertise at NIST, the Library of Congress has asked us to design and build a large encasement for a special map, the Waldseemueller Map. The Library of Congress purchased the only remaining copy of this historic map printed by map maker Martin Waldseemueller in 1507. This map is the first world map that shows our continent and names it “America” and thus it is often referred to as “America’s birth certificate.” Using a design that draws heavily on our Charters experience, we are finalizing this design and starting the fabrication of a large map encasement that is scheduled for completion in the summer of 2007. Many NIST employees have made contributions to this work and this presentation will highlight the science and engineering required for special document encasements. Richard Rhorer was contacted by the Library of Congress in 2005 and began discussions that lead to NIST undertaking the Waldseemueller map project starting in the fall of 2006. Rhorer is a mechanical engineer (MSME from the University of New Mexico 1967) and came to NIST in 1995 as the Shops Division Chief and is currently a researcher in the Manufacturing Metrology Division. He was the co-leader of the Charters project (with Chris Evans) to design and build the U.S. Charters of Freedom encasements and he has talked to several different audiences about this project in the years since. Rhorer is also currently discussing a potential NIST project with the Massachusetts Archives to design sealed document encasements for some important documents to be displayed at their museum in Boston.
Richard Rhorer , NIST Manufacturing Metrology Division, Gaithersburg, MD, richard.rhorer@nist.gov.
Administration Bldg, Lecture Rm. A. (NIST Contact: John Slotwinski, 301-975-2171, john.slotwinski@nist.gov)


ADVANCE NOTICE

3/8/07 10:30 AM - NIST COLLOQUIUM SERIES : Nanomedicine: Nanotechnology for Enhancing Human Health
NOTE: ****DIFFERENT DATE***** The application of nanotechnology to the prevention and treatment of human diseases holds great promise, but nanomaterials must be biocompatible, non-toxic and functional in biologic (wet) conditions, and well enough defined for acceptance by regulatory agencies. Early applications of nanomaterials will likely involve the development of medications that take advantage of unique aspects of nanostructures to achieve or enhance therapeutic activity. Examples will be given for the design, synthesis, and analysis of nanomaterials having attached molecules that allow for unique therapeutic functions. Applications include antimicrobial compounds, drug and gene delivery, and functional imaging. Concepts for future applications such as cellular engineering, human performance augmentation, and genetic manipulation for the treatment of human disease will be presented.
James Baker, Jr., M.D. , Director, Nanotechnology Institute for Medicine and the Biological Sciences, University of Michigan.
Administration Building, Red Auditorium. (NIST Contact: Kum Ham, 301-975-4203, kham@nist.gov)
Special Assistance Available

---

MEETINGS ELSEWHERE


2/26 -- MONDAY

No Scheduled Events

2/27 -- TUESDAY

4:15 PM - THE JOHNS HOPKINS UNIV. CHEMISTRY DEPT/ EPHRAIM AND WILMA SHAW ROSEMAN COLLOQUIUM SERIES: DESIGN OF NEW NITROXYL (HNO) DONORS FOR TREATMENT OF HEART FAILURE
K. Miranda , Univ. of Arizona.
Bldg, Rm. .
Chemistry Dept., The Johns Hopkins Univ., Baltimore, MD. (NIST Contact: R. Elder, 410-516-7432, rosalie@jhu.edu)



2/28 -- WEDNESDAY

No Scheduled Events

3/1 -- THURSDAY

No Scheduled Events

3/2 -- FRIDAY

No Scheduled Events

ADVANCE NOTICE

No Scheduled Events

---

TALKS BY NIST PERSONNEL

LINSTROM, P. : USING ANIML TO PUBLISH DATA ON THE INTERNET.
PITTCON 2007, Chicago, IL, 2/26.

GERMER, T. : MODELING THE EFFECT OF LINE AND TRENCH PROFILE VARIATION ON SCATTEROMETRY MEASUREMENTS.
Metrology, Inspection and Process Control for Microlithography Conference, San Jose Convention Center, San Jose, CA., 2/27.

BENNETT, H. : OPPORTUNITIES AND CHALLENGES FOR WIRELESS TECHNOLOGIES: PERSPECTIVES FROM THE ITRS AND USMS.
International Technology Roadmap for Semiconductor (ITRS)., Greensboro, NC USA, 2/27.

SCHULTZ, Z. : VIBRATIONAL SPECTROSCOPIC STUDIES OF MODEL BIOMEMBRANES.
Pittcon Conf. and Expo 2007, Chicago, IL, 2/28.

WOODWARD, J. : COMPONENT SEGREGATION IN MODEL CHEMICALLY AMPLIFIED RESISTS.
SPIE - Advance Lithography 2007, San Jose Convention Center, San Jose, CA, 2/28.

ZEISLER, R. : CHEMICAL CHARACTERIZATION OF A CANDIDATE CARBON NANOTUBE REFERENCE MATERIAL.
PITTCON, Chicago, IL, USA, 2/28.

HIGHT WALKER, A. : ASSEMBLY AND CHARACTERIZATION OF NANOCOMPLEXES: QUANTUM DOT ENCAPSULATED LIPOSOMES.
Biophysical Society, Baltimore Convention Center, Baltimore, MD, 3/3.

SCHULTZ, Z. : VIBRATIONAL INFRARED SPECTROSCOPIC STUDIES OF MODEL BIOMEMBRANES: CHARACTERIZATION OF LIBID RAFT FORMATION..
Biophysical Society 51st Annual Meeting, Baltimore Convention Center, Baltimore, MD, 3/4.

---

ANNOUNCEMENTS

BLACK HISTORY MONTH EVENT HONORING DR. PERCY L. JULIAN
Honoring Dr. Percy L. Julian 1:45pm Welcoming Remarks Dr. William Jeffrey, Director, NIST Commentary - Dr. James P. Shoffner, American Chemical Society - Dr. Bernhard Witkop, National Academy of Science 2:00pm Airing of Documentary NOVA “Percy Julian: Forgotten Genius” 4:00pm Gaithersburg, MD Attendee’s Reception Employee Lounge
NIST Contact: Willie may, 301-975-8300, wem@nist.gov

2007 INTERNATIONAL CONFERENCE ON FRONTIERS OF CHARACTERIZATION AND METROLOGY FOR NANOELECTRONICS--------------------------------------------REGISTER TODAY!
March 27-29, 2007 National Institute of Standards and Technology, Gaithersburg, Maryland Industry, government, and academia unite to present the latest advances related to frontier, state of the art materials and device characterization and metrology! Attend the 2007 International Conference on Frontiers of Characterization and Metrology for Nanoelectronics! The conference is scheduled for March 27-29, 2007, at the National Institute of Standards and Technology, Gaithersburg, USA. Please visit our conference website at http://www.eeel.nist.gov/812/conference/ for more information and/or to view the conference program. Let your voice be heard with those of our industry leaders. Join with Mark Durcan, COO of Micron; Michel Brillouett, Deputy Director of CEA/LETI; Hisatsune Watanabe, President and CEO of Selete; and Dan Hutcheson, CEO and President of VLSI Research Inc., as we examine the latest advances in characterization and metrology that will help shape the future of the nanoelectronics revolution. NIST REGISTRATION: All payments for advanced registration ($475) and student registration ($200) must be received by March 8, 2007. A late registration ($600) will be offered to attendees registering after March 8th, but no later than March 22, 2007. There will be no on-site registration. The registration fee includes coffee breaks, lunches, a reception, two evening dinner events, an extended abstract booklet, and the hardback book containing the workshop proceedings, along with a CD-ROM. The committee of the 2007 International Conference on Frontiers of Characterization and Metrology for Nanoelectronics is pleased to accept payment by either check (make checks payable to "Semiconductor Characterization Conference") or credit card (MasterCard or Visa). We have provided a text-based registration form under the "Registration" heading of our Conference Web page (http://www.eeel.nist.gov/812/conference/) that may be printed and mailed or faxed with all of your payment information. Or, if you would prefer, you may contact Brenda Main, our conference contractor, (see contact information below) and pay via MasterCard or Visa over the phone. CONTACT: Brenda Main Phone: (910) 620-5165 FAX: (910) 799-0323 e-mail: blmain22@yahoo.com. Requests for cancellation and refund must be received in writing by March 8, 2007.
NIST Contact: David Seiler, 301-975-2054, david.seiler@nist.gov

VISITOR REGISTRATION FOR NIST EVENTS
Because of heightened security at the NIST Gaithersburg site, members of the public who wish to attend meetings, seminars, lectures, etc. must first register in advance. For more information please call or e-mail the "NIST Contact" for the particular event you would like to attend.
NIST Contact: . ., ., .

---

NIST WEB SITE ANNOUNCEMENTS

SOURCE CODE SECURITY ANALYZERS
A source code security analyzer finds weaknesses in source code that can lead to security vulnerabilities. This web site lists dozens of such tools and has a draft specification, SP 500-268, which is now open for comment.
NIST Contact: Paul E. Black, 301-975-4794, paul.black@nist.gov

---

For more information, contact Ms. Sharon Hallman, Editor, Stop 2500, National Institute of Standards and Technology, Gaithersburg MD 20899-2500; Telephone: 301-975-TCAL (3570); Fax: 301-926-4431; or Email: tcal@nist.gov.

All lectures and meetings are open unless otherwise stated.

---

NVL Webmaster